AP23490015 Design, synthesis and chemical transformation of cyclic amidine systems and their conjugates with naturally occurring acids for biomedical applications

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AP23490015 Design, synthesis and chemical transformation of cyclic amidine systems and their conjugates with naturally occurring acids for biomedical applications

Project manager

Turmanov Rakhimzhan Akhmetkhanovich

Candidate of Chemical Sciences

Names of priority and specialized scientific areas

The intellectual potential of the country in the field of «Natural SciencesThe intellectual potential of the country in the field of "Natural Sciences"

Project goal

The goal of the project is to create a synthetic platform for the production of new types of functionally substituted amidine-like systems, based on new reactions:

1) N-arylation of cyclic, non-cyclic amidines and their surrogates with azine-N-oxides;

2) conjugation of natural triterpenoid acids and privileged imidazoline fragments, and other amidine rings for use as broad-spectrum therapeutic agents.

The amount of financing

120000000,0 tg

Implementation period

2024-2026 yy.